Osteopetrosis in twin infants mimicking leukemia
نویسندگان
چکیده
Osteopetrosis (OP) variably referred to as ‘Marble bone disease’ or ‘Albers Schonberg disease’ was first described by a German radiologist in 1904. It is a group of genetically and clinically heterogeneous disorders characterized by increased skeletal density. Clinical severity varies from asymptomatic adults to a life-threatening condition in infants. Autosomal recessive osteopetrosis has an incidence of 1 in 250,000 births while the dominant form has an incidence of 1 in 20,000 births.1 We report on twin infants with osteopetrosis presenting a leukoerythroblastic picture and hepatosplenomegaly mimicking leukemia.
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